background: approximately 10-14% of the clinically acknowledged pregnancies end with spontaneous abortion at caucasian population. possible immunologic causes of recurrent miscarriages have been extensively researched. the change in the cytokines balance synthesis in favor of those synthesized by th2 cells with an increase of interleukin 6 (il6) and interleukin10 (il10) secretion is considered ...

conclusions: we determined a significant higher frequency of protein s deficiency in patients with rpl compared with controls. but the frequency of protein c deficiency and the frequency of two common thrombophilic mutations (factor v leiden and prothrombin g20210a), were not significantly different between patients with recurrent miscarriage and healthy women. results: the mean functional acti...

background & aim: one of the factors of affecting maternal anxiety is a history of fetal death or neonatal death. this anxiety affects fetal and maternal health. by consideration the impact of anxiety on fetal and maternal health and the lack of protective activities in this field, this study was done to determine the impact of adaptation with pregnancy educational package on anxiety and matern...

osteoporosis is considered as an important public health problem especially in postmenopausal women. there are some hypotheses support the contributory effect of pregnancy and lactation on osteoporosis later in life. high calcium demand during pregnancy and lactation and low estrogenic state support those hypotheses. numerous studies have investigated on the issue but there is no consensus abou...

background: mitochondrial transfer rnas (trna) genes are essential components of protein biosynthesis. these genes are hotspots for mutations. these mutations are associated with a wide spectrum of human disease. many genetic factors are known in assessment of repeated pregnancy loss (rpl). objective: the aim of this study was analysis of trna thr and trna pro in women with rpl. materials and m...

background: in 2-4% of couples in fertile ages, recurrent pregnancy loss (rpl) occurs which consisted one out of 300 pregnancies. the aim of this study was to comparison insulin resistance (ir) in patients with rpl to normal individuals. materials and methods: in a case-controlled, prospective study, 49 non-pregnant, non-diabetic women with early rpl as the case group and 49 non-pregnant, non-d...

the purpose of this study was to determine whether sectioning the cervical septum is associated with intraoperative bleeding, incompetent cervix, and secondary infertility. in this prospective observational study, fourteen women with complete septate uterus who had a history of repeated pregnancy loss and infertility were treated hysteroscopically. preoperative history included 35 pregnancies o...

background: recurrent pregnancy loss is (rpl) a heterogeneous condition. while the role of acquired thrombophilia has been accepted as an etiology for rpl, the contribution of specific inherited thrombophilic gene polymorphisms to the disorder has been remained controversial. methods: one hundred women with a history of two or more consecutive abortions and 100 women with at least two live birt...